Enzyme-potentiated desensitisation (EPD) is very effective for treating food and other enviromental sensitivities. In addition, it is extremely useful in the treament of ME, since it works as an immune system modulator.

During EPD, a small quantity of a food or inhalant allergen mixture is injected intradermally into the skin, in conjunction with the enzyme beta-glucuronidase. This combination causes the body to gradually adjust its exaggerated responses to food and other environmental allergens. In this way, the immune system is readjusted and reset. This modulatory effect is of great value in treating ME.

Initially, the injections have to be given once every two months. Gradually, however, the intervals between injections become longer and the injections can often be discontinued after a time. According to conservative estimates, at least 80% of those patients treated with EPD show considerable improvement in the course of time.